Search results for "monoclonal antibody therapy"

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VEGF-B as a target for cancer therapy : characterization of monoclonal antibodies towards VEGF-B and generation of VEGF-B expressing tumour cell lines

2007

Vascular Endothelial Growth Factor Btumour angiogenesismonoclonal antibody therapysyöpävasta-aineetVEGF-B
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DC specific Smad7 deficiency promotes differentiation of tolerogenic DCs able to attenuate EAE

2014

The immune network is a complex system for host defenses comprising various types of inflammatory and regulatory cells. Autoimmune diseases occur because of dysregulation in homeostasis caused by imbalance of these cells. The pattern of imbalance depends on the disease. Most autoimmune diseases are chronic, and the mechanism underlying this chronic nature is yet to be determined. Monoclonal antibody therapy is highly specific to the molecules targeted and is therefore highly effective. However, this therapy cannot be applied to all autoimmune diseases, and even the most effective therapy is incapable of completely inhibiting disease activity. Antigen-specific therapies have the ability to i…

business.industryEffectorMultiple sclerosisImmunologyExperimental autoimmune encephalomyelitisCellDiseasemedicine.diseasemedicine.anatomical_structureNeurologyDownregulation and upregulationAntigenImmunologyImmunology and AllergyMedicineNeurology (clinical)businessMonoclonal antibody therapyJournal of Neuroimmunology
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